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However, because the disease can be transmitted to other people through contaminated blood and organs, most laboratories currently test donated blood and organs for transplantation for Chagas disease using avapro enzyme-linked immunosorbent assay.

In most cases, Chagas disease is diagnosed incidentally when people give blood because most people are unaware that they have been infected with T. cruzi.

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The chronic phase of Chagas disease is also diagnosed using avapro pills tests, but such patients often have a specific physical condition that indicates that the patient has a chronic disease. Physical findings may include swelling of the extremities (peripheral oedema), ascites, pulmonary edema, and arrhythmias in patients with cardiac injury. Patients with a chronic phase predominantly affecting the gastrointestinal tract may experience weight loss, severe gastric reflux, esophageal erosions, inability to swallow normally, or an enlarged colon (megacolon) with an enlarged abdomen.

Various diseases can cause these physical disorders, so it is important to know that a patient has a positive blood test for T. cruzi before a diagnosis of Chagas disease can be made. Conversely, if such physical findings and a history of possible contact with carriers of avapro infection are present, then a blood test can be done to prove or rule out a diagnosis of Chagas disease in the chronic phase. Other tests such as electrocardiography and Holter monitoring or cardiac monitoring, endoscopy, esophageal manometry (measurement of pressure in the esophagus), or gastrointestinal motility studies are used to determine the functionality of the heart and gastrointestinal tissues in patients with chronic phase Chagas disease.

What is the treatment for Chagas disease?

  • During the intermediate or indeterminate phase, the vast majority of irbesartan patients receive no antiparasitic treatment, however, children at this stage of the disease should continue therapy
  • The situation for adults may change after the end of irbesartan drug trials that are being conducted in South America
  • Antiparasitic drug therapy for the chronic phase in adults is controversial
  • As noted above, the CDC believes that adults with chronic infection may benefit from drug treatment, but most experts believe that adult patients with chronic Chagas disease offer no benefit
  • However, treatment of the symptoms of chronic Chagas disease is often necessary and may be life-saving or life-prolonging
  • For example, placement of a pacemaker or even a heart transplant can save the life of some patients who develop arrhythmias or cardiomyopathies
  • Surgical resection of the gastrointestinal tract can help relieve some gastrointestinal problems
  • In addition, there are many medications available to treat specific arrhythmias and other bowel problems that can develop in the chronic phase of Chagas disease
  • Often, heart and gastrointestinal specialists can help control and relieve symptoms of the chronic phase of Chagas disease

Can transmission of Chagas disease be prevented by a vaccine? There is currently no vaccine that can prevent Chagas disease. However, there are other ways available to everyone that help reduce the risk of infection or even prevent disease. Most Chagas disease experts agree that most infections can be prevented by improving poor or primitive living conditions.

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Prudent use of insecticides and home hygiene education designed for risk groups for Chagas disease can increase protection against the disease. The principle of popularizing this method is to prevent the creation of a cycle in the place of residence by bedbugs in the house, making it difficult for it to enter the house and reproduce in the dwelling. For example, high-quality plastering of walls, sealing the roof with metal or flexible tiles reduce the likelihood of insects settling in the house.
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The opposite situation occurs with a loose and unhygienic structure of the walls, roofing with straw, which provides insects with the opportunity to settle and breed in such premises.

Some research suggests that home hygiene is the most effective way to prevent Chagas disease.

Since blood transfusions can be attributed to the large amount of person-to-person transmission of T. cruzi, many blood banks around the world are now testing donated blood for antibodies to the parasite. If the blood test is positive, the blood is destroyed and donors are usually notified and asked not to donate blood in the future. Similar situations occur with organ donors. Such methods help prevent Chagas disease.

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What are the risk factors for Chagas disease?

In general, the prognosis for those who do not develop the chronic phase of Chagas disease is generally good. People who are diagnosed and treated in the acute phase of the disease also tend to have a favorable prognosis. However, people who develop the chronic phase of Chagas disease have a worse prognosis due to the damage done to the heart and gastrointestinal tract. What are the complications of Chagas disease?

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What is the prognosis for Chagas disease?

Most of the complications that develop with Chagas disease occur during the chronic phase of the disease. Most complications are associated with changes in muscle tissue (muscle wasting, fibrosis, and inflammation) caused by parasites that multiply in the heart and gastrointestinal tract. Thus, heart failure and esophageal and colonic dilatation (megaesophagus and megacolon) are serious complications in Chagas disease. These changes can lead to weakness, difficulty swallowing, abdominal pain, and death. Other organs can also be affected by the disease (ureters, bile ducts, for example).

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